
Josh Tetrick.
(Beth Clifton collage)
Cloned product will not be grown in serum culture, Tetrick says
SAN FRANCISCO––Hampton Creek Foods founder Josh Tetrick, amid a mysterious destocking of all 20 Hampton Creek products by Target Corporation, the largest Hampton Creek customer, took a meme of unknown origin attacking cell-cultured meat seriously enough to call at 5:02 p.m. on Friday, July 7, 2017 in reply to an inquiry from ANIMALS 24-7 sent just 12 minutes earlier––almost a record fast response from a corporate executive.

(Beth Clifton collage)
Message off Target
The 1,800 Target stores on June 23, 2017 abruptly quit selling anything from Hampton Creek, for reasons clear neither then nor now.
Reported Bloomberg News, “A Target spokeswoman said the company received allegations of food safety concerns as well as accusations of manipulation and adulteration of Hampton Creek’s products,” but more than two weeks later the U.S. Food & Drug Administration had not issued any related advisories and, Tetrick told ANIMALS 24-7, none of the other major Hampton Creek customers had followed Target’s lead.

Josh Balk & Josh Tetrick, partners in founding Hampton Creek Foods.
Why the meme mattered
While the $5.5 million Target account was of immediate concern to Tetrick, responding to the anti-cell cultured meat meme was also a priority, because the meme struck at what may be the longterm future of not only Hampton Creek Foods, but also what Tetrick and many others believe will be the future of the entire food industry.
Cell-cultured meat is not a big “profit center” for Hampton Creek Foods. Indeed, cell-cultured meat is not even among the 20-odd Hampton Creek products––yet.
But food research and development companies around the world are competing to be first to market a cultured meat product that appeals to consumers and can be produced on the scale necessary to capture a mass consumption niche.

“Fried ‘chicken’ from cells grown in culture by Memphis Meats,” a Hampton Creek rival. (Memphis Meats photo)
Cell-cultured chicken
“By the end of next year, we’ll have something out there on the marketplace,” Tetrick recently told Chase Purdy of the online magazine Quartz.
The “something out there on the marketplace” is likely to be a cell-cultured edition of chicken, the animals accounting for the most market share in U.S. meat consumption, dominating the fast food and prepared meal sectors.
Among land animals, none are consumed even remotely as often as chickens. Only fish––all fish species combined––account for more lives consumed by humans. Globally, counting by individual species, only pigs account for more poundage of human consumption than chickens. Cattle are a distant third, then sheep, goats, and turkeys.
“First will be in the avian family”
“We’ll do them all. First will be in the avian family,” Tetrick told ANIMALS 24-7.
Tetrick’s statement could include, as well as chickens, turkeys, ducks, or quail, among other birds commonly raised for human consumption.
Asked, “Chicken or turkey, we presume, with archaeopteryx not to follow until more of the technical issues are resolved?”, Tetrick answered only “That’s confidential for now.”
But cultured chickens were what Tetrick talked about.

Rosa, vegan activist Robert Grillo’s chicken.
(Facebook photo)
“It isn’t synthetic”
“We don’t like to talk about “synthetic” chicken,” Tetrick said, “because it isn’t synthetic. It’s real chicken meat. It is just produced in a different way.”
Reminded that chickens in conventional definition are complete animals, walking on two legs, with two wings, two eyes, and a sentient brain, Tetrick acknowledged that cultured meat will challenge lexicographers, who write dictionaries, as well as challenging the meat industry.
Cultured meat is already challenging vegans and vegetarians, even before any cultured meat products reach the marketplace.
The central question, for most, is whether any animal use, exploitation, or suffering will go into making cultured meat.
“Is lab grown meat vegan?”
Succinctly, as Bite Size Vegan blogger and YouTube channel producer Emily Moran Barwick of Northampton, Massachusetts put it in April 2016, “Is lab grown meat vegan?”
Ironically, by some definitions, the products Hampton Creek is developing may be “vegan” without being “vegetarian.”
Vegan Society founders Donald and Amy Watson coined the word “vegan” in 1944, initially to distinguish what the Watsons a first termed “non-dairy vegetarians” as a faction within the Vegetarian Society.

Donald Watson. (Vegan Society photo)
Donald Watson (1910-2005) eventually expanded the definition of vegan to include avoiding the use of animals and animal byproducts for any purpose, including food, clothing, entertainment, transportation, and other work.
Vegan but not vegetarian?
But the original definition of “vegan,” meaning simply food of entirely non-animal origin, had already gained traction, leading to endless debate ever since among vegans, would-be vegans, and “vegan police” trying to enforce rigid standards about what is what.
Cultured meat is particularly problematic because it promises to be real meat at the molecular level, yet not directly of animal origin and therefore not directly implicated, if at all, in animal exploitation or suffering. Because it is meat, it could not be considered vegetarian, yet because animals are not involved in producing it, it might be vegan.

Celebrity homemaker Martha Stewart and Josh Tetrick. (Facebook photo)
But the meme ANIMALS 24-7 received, apparently widely posted on Facebook in response to announcements from Hampton Creek and smaller rival Memphis Meats about their progress in developing cultured meat products, alleges otherwise.
No “donor herds”
Headlined “The Victims of Lab Grown Meat,” the meme asserts that “A ‘donor herd’ will be kept to replace the cells [used to produce cultured meat] when the DNA has degraded. A herd will be needed for each kind of meat.”
The meme further alleged that cultured meat will be grown in a medium of calf fetal serum.
The allegations, Tetrick explained to ANIMALS 24-7, could scarcely be more incorrect.
“You could get all the animal cells we need from a feather,” Tetrick said. “You just cut off the quill tip of a naturally discarded feather, and there is all the cell structure we need. Then we grow the product in a culture developed entirely from plant extracts. There will not be any ‘donor herds’ nor any need for any. You could pick up all the animal cells we need just by picking up the shed feathers at a sanctuary.”

Emily Moran Barwick with meme based on her blog.
Outdated information about a different process
The source of the meme claims appears to have been the Moran Berwick posting “Is lab grown meat vegan?”, but the posting relied on outdated information about an entirely different process, used for an entirely different purpose.
A lifelong meat avoider and vegan activist throughout her adult life, Emily Moran Barwick began blogging and making videos to promote a vegan lifestyle in 2013, gradually building a YouTube audience of upward of 100,000. She appears to have made a conscientious effort in “Is lab grown meat vegan?” to be fair and accurate, looking at all sides of the issues to the extent of providing footnotes for each statement––and the footnotes establish how she garbled the issue.

Hereford calf & mother. (Beth Clifton photo)
A “major ethical issue”
A “major ethical issue,” Moran Barwick wrote, “is the growth medium into which the cells are deposited” to culture a meat product. “At the moment, the most widely used medium is bovine fetal serum.”
Her sole source for this, and for all of the gruesome claims about how bovine fetal serum is collected, was “The use of fetal bovine serum: Ethical or scientific problem?,” by the Dutch scientist Carlo E.A. Jochems, published in March 2002 in the peer-reviewed journal Alternatives to Laboratory Animals. The journal is funded by the British-based Fund for the Replacement of Animals in Medical Experiments.

(Merritt Clifton collage)
Apart from 2002 being practically the Dark Ages in terms of the development of cultured meat, and in terms of cell culturing generally, Jochems’ article described cell culturing performed on a relatively small scale, as had been done for decades in connection with biomedical research and testing.
Transition point
Jochems wrote at a transition point.
Commercial and scientific demand for cell cultures of various sorts was then rapidly expanding beyond the capacity of the existing production systems.
Simultaneously, the risks from pathogens contaminating experiments through the use of bovine fetal serum were becoming recognized.
Finally, as Jochems spotlighted, concern was growing within the scientific community about the ethics of processes which are either painful to animals or distressing to humans who become aware of them.

Josh Tetrick (left) with Farm Sanctuary founder Gene Baur (right).
On the way out
There is still a bovine fetal serum production industry, but the use of bovine fetal serum in leading-edge in science was already on the way out by 2009, when an international conference was convened in Copenhagen, Sweden, “to discuss strategies to improve the development and use of serum-free defined media,” reported ten co-authors in the journal Toxicology in Vitro.
Bovine fetal serum was used in some of the earliest experimental attempts to develop cultured meat. As recently as 2011, reported Scott Canon of the Kansas City Star, all experimental cultured meat products, none bigger than marbles, had been “sustained by animal products, typically fetal bovine serum.”
However, before before cultured meat development could advance, Canon explained, “A replacement needs to be found, to get the efficiencies that make the new meat worth the bother, and to gain consistency and safety from pathogens.”

Josh Tetrick & Jake, his chief cultured meat quality advisor. (Facebook photo)
Breakthrough
This is the breakthrough that Hampton Creek Foods, Memphis Meats, and other leaders in cultured meat development believe they have achieved.
Outlines the Hampton Creek Foods web site http://www.eatjust.com/en-us/stories/just-plan, “Most of the world’s 353,000 plant species are unexplored. Collectively, they make up 18 billion proteins, 108 million fats, and four million carbohydrates. If efficiently distributed, a protein discovery in one bean (for example) can improve multiple billion-dollar food categories.
“We’ve already sourced diverse plants from over 51 countries,” the EatJust site continues, “with more added to our library weekly. First, we started analyzing their protein content by hand. Now, we’re building our automated discovery platform—using robotics and machine learning—to explore their potential faster. The more data we gather, the more we’ll discover proteins, fats, and carbohydrates in plants that will improve the food system.

Just Mayo goes down well with vegan hot dogs. (Hampton Creek image)
The meat of the matter
“As our hit rate accelerates,” EatJust says, “we’ll continue applying these plants to our current and new product categories, including eggs, butter, shortening, milk, baked goods, pasta, condiments, snacks, and micronutrient-rich products for billions of people in developing countries.”
Getting to the meat of the matter, the EatJust page explains, “As we researched more of the functional potential of plants, we’ve found that they can do even more: they can enable animal cells to grow sustainably and efficiently.
“Over the past year,” EatJust adds, “we’ve started the early work of expanding our platform to solve the technical challenges of scalable clean meat. Clean meat and seafood are made from cells instead of live, confined animals.

(Beth Clifton photo)
Muscle & fat cells
“Here’s how: meat and seafood are primarily a combination of muscle and fat cells. They require nutrients to grow, whether inside an animal or in a clean facility. And the main limiting factor in scaling clean meat has been providing cells with a sustainable and economical source of nutrients required for cell growth.
“Our methodology of discovery (material isolation, assays, and discovery output) is the same whether we’re finding a plant to replace dairy in butter or a plant to feed cells for clean and sustainable meat and seafood,” EatJust says, and then comes to the bottom line:
“With plants providing nutrients for animal cells to grow, we believe we can produce meat and seafood that is over 10 times more efficient than the world’s highest volume slaughterhouse (a million-square foot facility in Tar Heel, N.C.). All this without confining or slaughtering a single animal and with a fraction of the greenhouse gas emissions and water use.”

(Beth Clifton photo)
Algae & mushrooms
Acknowledged Moran Barwick, “The champions of the cultured meat movement seem to be invested in finding plant-based medium alternatives with both algae and mushrooms providing promising options.”
Meanwhile, Moran Barwick wrote, “The vegan community is most dramatically torn. Some feel that any product derived from an animal remains a form of exploitation. Others believe that with the insurmountable fight against the ongoing animal holocaust and more non-vegans being born every day, we need to search for practical and viable solutions to replace humanity’s rising demand for meat. The vegans on the pro-cultured meat side say their motivation is putting the animals’ interests above all else.”

Merritt & Beth Clifton
Concluded Moran Barwick, “Providing an alternative that not only looks and tastes like but actually is meat could be, with the proper harvesting method and growth medium, the most immediate path to animal liberation currently available.”
For the reasons outlined in this article, whatever ambivalence I initially felt about cultured laboratory meat, especially because of early concern that such meat would require the keeping of live animals as perpetual “seed,” I am now firmly in the camp of the “others,” as per below. Thank you for this extremely informative and helpful article. I am sorry to read about Target’s mysterious decision and hope for speedy restoration of Hampton Creek food products in Target stores.
“The vegan community is most dramatically torn. Some feel that any product derived from an animal remains a form of exploitation. Others believe that with the insurmountable fight against the ongoing animal holocaust and more non-vegans being born every day, we need to search for practical and viable solutions to replace humanity’s rising demand for meat. The vegans on the pro-cultured meat side say their motivation is putting the animals’ interests above all else.”
Karen Davis, PhD, President, United Poultry Concerns http://www.upc-online.org
Josh is absolulty correct. Insread of cloning I might call it an immortalized vstem cell line. I posted on Hamton Creeks facebook page and got all these strange replies about harm to animals. I find it silly anyway because if indeed these posters are militant vegans ….they dont have to eat it. I suspect some aspect of legacy meat industry and I urge a wall street solution to this. Memphis meat has published its breakthroughs on stem cell lines and growth medium in Nature. This was from funding in part by PETA. . This is meat under the legal and regulatory definition it is just a different way to make it. The claim of an SEC investigation was also strange because Hamton Creek is pivate, not public. Its Venture backed so I cant see how the SEC could investigate everythjng. One animal friendly company that is also under attack is SenesTech. That seems to be short sellers. I bought SensesTech stock and I’m down a couple of dollars. We live in an age of disinformation so its good Hamton Creek is fighting back. It is sad this overshadows their big breakthoughs in the field.
Thank you for helping to clarify this issue. It sounds promising, and such success should be welcomed if for no other reason that for the ability to produce meat for house cats and other carnivores who are dependent on humans for their food.
As for Target, I wonder if Hampton Creek might have grounds to sue the corporation for the seemingly baseless disparagement of their products.
Not an expert, so I can’t claim to know the minutae of the process. But on the face of it, I’m extremely excited by something that could replace factory-farm-derived meat and other products derived as a result of animal suffering and death. There are so many people globally who choose to eat meat and who will probably never be ethical vegetarians or vegans. Replacing the products they now buy or use with these products — think of the reduction in suffering and death, not to mention, from the human-concern standpoint, the massive downsizing through natural attrition of the “herds” which now produce methane and other effluent on such large scale that they are damaging our global infrastructure.
I’m in complete agreement with Mary Finelli posting before me, as well, because I will always care for and feed cats, and as obligate carnivores, they need meat.
It would be interesting to know exactly what Target’s reasons are for pulling Hampton Creek’s products.
Lots of people are against red meat as not being healthy for people, and some are against any kind of meat (including fish) as not being good for people. This article doesn’t mention the people who think that, without mentioning concern about animals. Has this subject come up?
If cultured meat is, as it appears to be, identical in molecular structure to meat from actual animals, the health issues associated with eating either sort of meat would also be identical. However, Josh Tetrick and other developers of cultured meat products believe that many and perhaps most of the negative health effects from eating meat can somehow be engineered out of the cultured variety. Certainly, because cultured meats will be produced without the existence of an attached endocrine system, they will not contain hormonal chemicals, unless some are synthesized and added to provide flavor and texture.